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The Adaptor Proteins p66Shc and Grb2 Regulate the Activation of the GTPases ARF1 and ARF6 in Invasive Breast Cancer Cells

Signals downstream of growth factor receptors play an important role in mammary carcinogenesis. Recently, we demonstrated that the small GTPases ARF1 and ARF6 were shown to be activated downstream of the epidermal growth factor receptor (EGFR) and act as a key regulator of growth, migration, and inv...

詳細記述

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書誌詳細
主要な著者: Haines, Eric, Saucier, Caroline, Claing, Audrey
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937643/
https://ncbi.nlm.nih.gov/pubmed/24407288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.516047
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