The Prevalence and Molecular Spectrum of α- and β-Globin Gene Mutations in 14,332 Families of Guangdong Province, China

OBJECTIVE: To reveal the familial prevalence and molecular variation of α- and β-globin gene mutations in Guangdong Province. METHODS: A total of 40,808 blood samples from 14,332 families were obtained and analyzed for both hematological and molecular parameters. RESULTS: A high prevalence of α- and...

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Detalhes bibliográficos
Main Authors: Yin, Aihua, Li, Bing, Luo, Mingyong, Xu, Longchang, Wu, Li, Zhang, Liang, Ma, Yuanzhu, Chen, Tingting, Gao, Shuang, Liang, Juqing, Guo, Hao, Qin, Danqing, Wang, Jicheng, Yuan, Tenglong, Wang, Yixia, Huang, Wei-wei, He, Wen-Fei, Zhang, Yanxia, Liu, Chang, Xia, Sujian, Chen, Qingshan, Zhao, Qingguo, Zhang, Xiaozhuang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937408/
https://ncbi.nlm.nih.gov/pubmed/24587075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089855
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