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Highly Active Antiretroviral Therapies Are Effective against HIV-1 Cell-to-Cell Transmission

HIV-1 cell-to-cell transmission allows for 2–3 orders of magnitude more efficient viral spread than cell-free dissemination. The high local multiplicity of infection (MOI) observed at cell-cell contact sites may lower the efficacy of antiretroviral therapies (ART). Here we test the efficacy of commo...

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Autori principali: Agosto, Luis M., Zhong, Peng, Munro, James, Mothes, Walther
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937346/
https://ncbi.nlm.nih.gov/pubmed/24586176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003982
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