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Mechanistic Independence of Nef and Cyclophilin A Enhancement of Human Immunodeficiency Virus Type 1 Infectivity
Optimal HIV-1 infectivity requires the presence of both the viral factor Nef and the cellular protein cyclophilin A (CyPA) during virion assembly. These two proteins are integral components of HIV-1 particles. Both CyPA and Nef facilitate a step in the viral life cycle occurring between penetration...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1998
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937310/ https://ncbi.nlm.nih.gov/pubmed/9705263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/viro.1998.9254 |
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