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Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

BACKGROUND: Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. The objective of this randomized, double-blind, placebo-controlled, phase I trial was to determine the safety of intravenously infused ascorbic acid in patients wi...

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Detalhes bibliográficos
Main Authors: Fowler, Alpha A, Syed, Aamer A, Knowlson, Shelley, Sculthorpe, Robin, Farthing, Don, DeWilde, Christine, Farthing, Christine A, Larus, Terri L, Martin, Erika, Brophy, Donald F, Gupta, Seema, Fisher, Bernard J, Natarajan, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937164/
https://ncbi.nlm.nih.gov/pubmed/24484547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-32
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