A Novel Bayesian Method for Detection of APOBEC3-Mediated Hypermutation and Its Application to Zoonotic Transmission of Simian Foamy Viruses

Simian Foamy Virus (SFV) can be transmitted from non-human primates (NHP) to humans. However, there are no documented cases of human to human transmission, and significant differences exist between infection in NHP and human hosts. The mechanism for these between-host differences is not completely u...

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Main Authors: Matsen, Frederick A., Small, Christopher T., Soliven, Khanh, Engel, Gregory A., Feeroz, Mostafa M., Wang, Xiaoxing, Craig, Karen L., Hasan, M. Kamrul, Emerman, Michael, Linial, Maxine L., Jones-Engel, Lisa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937129/
https://ncbi.nlm.nih.gov/pubmed/24586139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003493
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