Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis

BACKGROUND: Recent studies demonstrated that engagement of sodium glucose transporter 1 (SGLT-1) by orally administered D-glucose protects the intestinal mucosa from lipopolysaccharide (LPS)-induced injury. We tested whether SGLT-1 engagement might protect the intestinal mucosa from doxorubicin (DXR...

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Main Authors: Cardani, Diego, Sardi, Claudia, La Ferla, Barbara, D’Orazio, Giuseppe, Sommariva, Michele, Marcucci, Fabrizio, Olivero, Daniela, Tagliabue, Elda, Koepsell, Hermann, Nicotra, Francesco, Balsari, Andrea, Rumio, Cristiano
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937063/
https://ncbi.nlm.nih.gov/pubmed/24495286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-23
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