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PAX5 fusion genes in t(7;9)(q11.2;p13) leukemia: a case report and review of the literature

BACKGROUND: B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by recurrent genetic alterations including chromosomal translocations. The transcription factor PAX5, which is pivotal for B-cell commitment and maintenance, is affected by rearrangements, which lead to the expressi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Denk, Dagmar, Bradtke, Jutta, König, Margit, Strehl, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937052/
https://ncbi.nlm.nih.gov/pubmed/24507461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-7-13
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