Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity

BACKGROUND: Considering previous result in Non-Small Cell Lung Cancer (NSCLC), we investigated in human cancer cells the role of PARP3 in the regulation of telomerase activity. METHODS: We selected A549 (lung adenocarcinoma cell line) and Saos-2 (osteosarcoma cell line), with high and low telomerase...

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Autori principali: Fernández-Marcelo, Tamara, Frías, Cristina, Pascua, Irene, de Juan, Carmen, Head, Jacqueline, Gómez, Ana, Hernando, Florentino, Jarabo, Jose-Ramon, Díaz-Rubio, Eduardo, Torres, Antonio-Jose, Rouleau, Michèle, Benito, Manuel, Iniesta, Pilar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937032/
https://ncbi.nlm.nih.gov/pubmed/24528514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-19
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