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Evaluation of 147 Kampo prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents

BACKGROUND: Protein tyrosine phosphatase (PTP) 1B, a negative regulator of the insulin and leptin signaling pathways, is currently considered a promising target for the development of novel therapeutic approaches used to treat insulin-resistant type 2 diabetes mellitus (IR-T2DM). In this study, we e...

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Detalhes bibliográficos
Main Authors: Onoda, Toshihisa, Li, Wei, Higai, Koji, Koike, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936919/
https://ncbi.nlm.nih.gov/pubmed/24555682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-64
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