Naproxen induces cell cycle arrest and apoptosis in human urinary bladder cancer cell lines and chemically induced cancers by targeting PI3-K

Naproxen ((S)-6-methoxy-α-methyl-2-naphthaleneacetic acid) is a potent nonsteroidal anti-inflammatory drug that inhibits both COX-1 and COX-2 and is widely used as an over-the-counter medication. Naproxen exhibits analgesic, anti-pyretic, and anti-inflammatory activities. Naproxen, as well as other...

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Hauptverfasser: Kim, Mi-Sung, Kim, Jong-Eun, Lim, Do Young, Huang, Zunnan, Chen, Hanyong, Langfald, Alyssa, Lubet, Ronald A., Grubbs, Clinton J., Dong, Zigang, Bode, Ann M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936888/
https://ncbi.nlm.nih.gov/pubmed/24327721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0288
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