ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia

Tumor-propagating cells in acute leukemia maintain a stem/progenitor-like immature phenotype and proliferative capacity. Acute myeloid leukemia (AML) and acute T-lymphoblastic leukemia (T-ALL) originate from different lineages through distinct oncogenic events such as MLL fusions and Notch signaling...

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Hlavní autoři: Weisberg, Stuart P., Smith-Raska, Matthew R., Esquilin, Jose M., Zhang, Ji, Arenzana, Teresita L., Lau, Colleen M., Churchill, Michael, Pan, Haiyan, Klinakis, Apostolos, Dixon, Jack E., Mirny, Leonid A., Mukherjee, Siddhartha, Reizis, Boris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936793/
https://ncbi.nlm.nih.gov/pubmed/24485662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.007
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