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ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia
Tumor-propagating cells in acute leukemia maintain a stem/progenitor-like immature phenotype and proliferative capacity. Acute myeloid leukemia (AML) and acute T-lymphoblastic leukemia (T-ALL) originate from different lineages through distinct oncogenic events such as MLL fusions and Notch signaling...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936793/ https://ncbi.nlm.nih.gov/pubmed/24485662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.007 |
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