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Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching

Hfq is a posttranscriptional riboregulator and RNA chaperone that binds small RNAs and target mRNAs to effect their annealing and message-specific regulation in response to environmental stressors. Structures of Hfq-RNA complexes indicate that U-rich sequences prefer the proximal face and A-rich seq...

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Autors principals: Robinson, Kirsten E., Orans, Jillian, Kovach, Alexander R., Link, Todd M., Brennan, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936774/
https://ncbi.nlm.nih.gov/pubmed/24288369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1171
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