Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing

Most mitotic homologous recombination (HR) events proceed via a synthesis-dependent strand annealing mechanism to avoid crossing over, which may give rise to chromosomal rearrangements and loss of heterozygosity. The molecular mechanisms controlling HR sub-pathway choice are poorly understood. Here,...

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Hlavní autoři: Paliwal, Shreya, Kanagaraj, Radhakrishnan, Sturzenegger, Andreas, Burdova, Kamila, Janscak, Pavel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936725/
https://ncbi.nlm.nih.gov/pubmed/24319145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1263
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