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Clones of cytotoxic T lymphocytes reactive to haptenated allogeneic cells: precursor frequency and characteristics as determined by a split-culture approach.

CBA (H-2k) responder spleen cells have been cultured at limit dilution with trinitrophenyl (TNP)-modified BALB/c (H-2d) stimulator cells and a source of T-cell growth factor in order to generate cytotoxic effector clones. After culture, such clones were split into two to four replicates and each was...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Good, M F, Nossal, G J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6132381/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.6.1693
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