Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses

Aims: The free radical scavenger and nitric oxide synthase cofactor, 5,6,7,8-tetrahydrobiopterin (BH4), plays a well-documented role in many disorders associated with oxidative stress, including normal tissue radiation responses. Radiation exposure is associated with decreased BH4 levels, while BH4...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pathak, Rupak, Pawar, Snehalata A., Fu, Qiang, Gupta, Prem K., Berbée, Maaike, Garg, Sarita, Sridharan, Vijayalakshmi, Wang, Wenze, Biju, Prabath G., Krager, Kimberly J., Boerma, Marjan, Ghosh, Sanchita P., Cheema, Amrita K., Hendrickson, Howard P., Aykin-Burns, Nukhet, Hauer-Jensen, Martin
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2014
Sujets:
Forum Original Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936502/
https://ncbi.nlm.nih.gov/pubmed/23521531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.5025
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