Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia

Postinfluenza pneumococcal pneumonia is a common cause of death in humans. However, the role of IL-27 in the pathogenesis of secondary pneumococcal pneumonia after influenza is unknown. We now report that influenza infection induced pulmonary IL-27 production in a type I IFN-α/β receptor (IFNAR) sig...

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Detalhes bibliográficos
Main Authors: Cao, Ju, Wang, Dongsheng, Xu, Fang, Gong, Yi, Wang, Hong, Song, Zixin, Li, Dageng, Zhang, Hua, Li, Dairong, Zhang, Liping, Xia, Yun, Xu, Huajian, Lai, Xaiofei, Lin, Shihui, Zhang, Xuemei, Ren, Guosheng, Dai, Yubing, Yin, Yibing
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936494/
https://ncbi.nlm.nih.gov/pubmed/24408967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302890
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