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Expression, purification, crystallization and preliminary X-ray analysis of full-length human RIG-I

The human innate immune system can detect invasion by microbial pathogens through pattern-recognition receptors that recognize structurally conserved pathogen-associated molecular patterns. Retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) are one of the two major families of pattern-reco...

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Bibliographische Detailangaben
Hauptverfasser: Kwok, Jane, Hui, Kenrie P. Y., Lescar, Julien, Kotaka, Masayo
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936451/
https://ncbi.nlm.nih.gov/pubmed/24637767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14000430
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