DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

DNA fragments 536 base pairs long differing by single base-pair substitutions were clearly separated in denaturing gradient gel electrophoresis. Transversions as well as transitions were detected. The correspondence between the gradient gel measurements and the sequence-specific statistical mechanic...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Fischer, S G, Lerman, L S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393645/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6220406/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.6.1579
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