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Formulation and Evaluation of Irinotecan Suppository for Rectal Administration
Irinotecan suppository was prepared using the moulding method with a homogeneous blend. A sensitive and specific fluorescence method was developed and validated for the determination of irinotecan in plasma using HPLC. The pharmacokinetics of intravenous administered and rectal administered in rabbi...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Society of Applied Pharmacology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936431/ https://ncbi.nlm.nih.gov/pubmed/24596626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2013.087 |
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