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A Conformational Switch in Bacteriophage P22 Portal Protein Primes Genome Injection

Double-stranded DNA (dsDNA) viruses such as herpesviruses and bacteriophages infect by delivering their genetic material into cells, a task mediated by a DNA channel called “portal protein.” We have used electron cryomicroscopy to determine the structure of bacteriophage P22 portal protein in both t...

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Detalhes bibliográficos
Main Authors: Zheng, Hongjin, Olia, Adam S., Gonen, Melissa, Andrews, Simeon, Cingolani, Gino, Gonen, Tamir
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936403/
https://ncbi.nlm.nih.gov/pubmed/18280242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.034
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