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Deciphering Genetic Disease in the Genomic Era: The Model of GnRH Deficiency

Congenital gonadotropin-releasing hormone (GnRH) deficiency is a treatable albeit rare form of reproductive failure that has revealed physiological mechanisms controlling human reproduction, but despite substantial progress in discovering pathogenic single-gene defects, most of the genetic basis of...

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Bibliographic Details
Main Authors: Sykiotis, Gerasimos P., Pitteloud, Nelly, Seminara, Stephanie B., Kaiser, Ursula B., Crowley, William F.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936248/
https://ncbi.nlm.nih.gov/pubmed/20484732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000288
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