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Ulinastatin Preconditioning Attenuates Inflammatory Reaction of Hepatic Ischemia Reperfusion Injury in Rats via High Mobility Group Box 1(HMGB1) Inhibition

Objective It has been found that ulinastatin (UTI) can attenuate hepatic injury in a rat model of ischemia reperfusion (IR), but the specific mechanism is unclear. This study aims to investigate possible pathomechanism of ulinastatin in reducing the inflammatory response after hepatic IR. Methods A...

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Détails bibliographiques
Auteurs principaux: Tong, Ying, Tang, Zhaohui, Yang, Tian, Yang, Yuting, Yang, Liqun, Shen, Weixing, Chen, Weixin
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936027/
https://ncbi.nlm.nih.gov/pubmed/24578610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.7861
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