INSULIN RESISTANCE AND BONE STRENGTH. FINDINGS FROM THE STUDY OF MIDLIFE IN THE UNITED STATES

BACKGROUND: While several studies have noted increased fracture risk in individuals with type 2 DM (T2DM), the pathophysiologic mechanisms underlying this association are not known. We hypothesize that insulin resistance (the key pathology in T2DM) negatively influences bone remodeling and leads to...

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Auteurs principaux: Srikanthan, Preethi, Crandall, Carolyn J., Miller-Martinez, Dana, Seeman, Teresa E., Greendale, Gail A., Binkley, Neil, Karlamangla, Arun S.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935990/
https://ncbi.nlm.nih.gov/pubmed/23983216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2083
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