Polymeric Micelles for Apoptosis-Targeted Optical Imaging of Cancer and Intraoperative Surgical Guidance

In a two-step strategy, an intraperitoneal (IP) injection of poly(ethylene glycol)-block-poly(ε-caprolactone) (PEG-b-PCL) micelles containing paclitaxel (PTX), cyclopamine (CYP), and gossypol (GSP) at 30, 30, and 30 mg/kg, respectively, debulked tumor tissues by 1.3-fold, based on loss of biolumines...

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Autors principals: Cho, Hyunah, Cho, Clifford S., Indig, Guilherme L., Lavasanifar, Afsaneh, Vakili, Mohammad Reza, Kwon, Glen S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935963/
https://ncbi.nlm.nih.gov/pubmed/24587157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089968
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