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Transient Replication of Hepatitis C Virus Sub-Genomic RNA in Murine Cell Lines Is Enabled by miR-122 and Varies with Cell Passage

Hepatitis C Virus (HCV) is a serious global health problem, infecting almost 3% of the world’s population. The lack of model systems for studying this virus limit research options in vaccine and therapeutic development, as well as for studying the pathogenesis of chronic HCV infection. Herein we mak...

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Autors principals: Thibault, Patricia A., Wilson, Joyce A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935951/
https://ncbi.nlm.nih.gov/pubmed/24587159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089971
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