Unsaturated Glycerophospholipids Mediate Heme Crystallization: Biological Implications for Hemozoin Formation in the Kissing Bug Rhodnius prolixus

Hemozoin (Hz) is a heme crystal produced by some blood-feeding organisms, as an efficient way to detoxify heme derived from hemoglobin digestion. In the triatomine insect Rhodnius prolixus, Hz is essentially produced by midgut extracellular phospholipid membranes known as perimicrovillar membranes (...

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Main Authors: Stiebler, Renata, Majerowicz, David, Knudsen, Jens, Gondim, Katia C., Wright, David W., Egan, Timothy J., Oliveira, Marcus F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935856/
https://ncbi.nlm.nih.gov/pubmed/24586467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088976
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