Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy

The aim of this study was to investigate the role of common polymorphisms in the NER pathway genes in the tumorigenesis of osteosarcoma and in the response to DNA damaging therapies, such as cisplatin-based neoadjuvant therapy. XPD (rs13181 and rs1799793), XPG (rs17655), and ERCC1 (rs3212986 and rs1...

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Bibliografische gegevens
Hoofdauteurs: Biason, Paola, Hattinger, Claudia Maria, Innocenti, Federico, Talamini, Renato, Alberghini, Marco, Scotlandi, Katia, Zanusso, Chiara, Serra, Massimo, Toffoli, Giuseppe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935514/
https://ncbi.nlm.nih.gov/pubmed/21826087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.33
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