A papillomavirus-like particle (VLP) vaccine displaying HPV16 L2 epitopes induces cross-neutralizing antibodies to HPV11

Peptides of the papillomavirus L2 minor capsid protein can induce antibodies (Ab) that neutralize a broad range of human papillomavirus (HPV) genotypes. Unfortunately, L2 is antigenically subdominant to L1 in the virus capsid. To induce a strong anti-L2 Ab response with cross-neutralizing activity t...

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Main Authors: Slupetzky, Katharina, Gambhira, Ratish, Culp, Timothy D., Shafti-Keramat, Saeed, Schellenbacher, Christina, Christensen, Neil D., Roden, Richard B.S., Kirnbauer, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935451/
https://ncbi.nlm.nih.gov/pubmed/17239496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.11.049
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