A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig

Electrical stimulation of the cervical vagus nerve in anesthetized guinea pigs induced a rapid increase in respiratory insufflation pressure, suggesting increased airway resistance. After intravenous administration of a substance P (SP) antagonist, [D-Arg(1),D-Pro(2),D-Trp(7,9),Leu(11)]SP, the insuf...

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Bibliografische gegevens
Hoofdauteurs: Lundberg, J. M., Saria, A., Brodin, E., Rosell, S., Folkers, K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
Onderwerpen:
Biological Sciences: Neurobiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC393540/
https://ncbi.nlm.nih.gov/pubmed/6189120
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