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Alzheimer disease: Aβ-independent processes-rethinking preclinical AD
The 20-year dominating amyloid cascade hypothesis posits that Aβ accumulation is the primary and causal event in Alzheimer disease neurodegeneration. Recent findings, however, show that neuronal-injury biomarkers are independent of Aβ. This will probably lead calling for reconsideration of the patho...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Pub. Group
2013
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3935395/ https://ncbi.nlm.nih.gov/pubmed/23399647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2013.21 |
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