Phosphodiesterase 4D Single-Nucleotide Polymorphism 83 and Cognitive Dysfunction in Carotid Endarterectomy Patients

BACKGROUND: Phosphodiesterase 4D (PDE4D), through the regulation of cyclic AMP, modulates inflammation and other processes that affect atherosclerosis and stroke. A PDE4D polymorphism, single-nucleotide polymorphism (SNP) 83 (rs966221), is associated with ischemic stroke. The association of SNP 83 w...

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Bibliografiske detaljer
Main Authors: Heyer, Eric J., Mergeche, Joanna L., Ward, Justin T., Malone, Hani R., Kellner, Christopher, Bruce, Samuel S., Connolly, E. Sander
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935380/
https://ncbi.nlm.nih.gov/pubmed/23863764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0000000000000085
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