Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brain.

The hypothesis that age-associated impairment of cognitive and motor functions is due to oxidative molecular damage was tested in the mouse. In a blind study, senescent mice (aged 22 months) were subjected to a battery of behavioral tests for motor and cognitive functions and subsequently assayed fo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Forster, M J, Dubey, A, Dawson, K M, Stutts, W A, Lal, H, Sohal, R S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4765
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