Activating KIRs in Chronic Lymphoproliferative Disorder of NK Cells: Protection from Viruses and Disease Induction?

Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I molecules. As KIR expression in a given NK cell is stochastically established, KIR repertoire perturbations reflect a dominance of discrete NK-cell s...

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Bibliografiske detaljer
Main Authors: Zambello, Renato, Teramo, Antonella, Barilà, Gregorio, Gattazzo, Cristina, Semenzato, Gianpietro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935213/
https://ncbi.nlm.nih.gov/pubmed/24616720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00072
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