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Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix.

Thrombospondin, a major glycoprotein released from alpha granules of thrombin-stimulated platelets, is a disulfide-bonded trimer of 160-kilodalton subunits. Cultured human foreskin and fetal lung fibroblasts secreted thrombospondin (determined by enzyme-linked immunosorbent assay) into the culture m...

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Autors principals: Jaffe, E A, Ruggiero, J T, Leung, L K, Doyle, M J, McKeown-Longo, P J, Mosher, D F
Format: Artigo
Idioma:Inglês
Publicat: 1983
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC393515/
https://ncbi.nlm.nih.gov/pubmed/6341993
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