An Ethinyl Estradiol-Levonorgestrel Containing Oral Contraceptive Does Not Alter Cytochrome P4502C9 In Vivo Activity

Oral contraceptives have been in wide use for more than 50 years. Levonorgestrel, a commonly employed progestin component of combined oral contraceptives, was implicated in drug–drug interactions mediated via CYP2C9. Although in vitro studies refuted this interaction, there are no confirmatory in vi...

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Detaylı Bibliyografya
Asıl Yazarlar: Cherala, Ganesh, Pearson, Jacob, Maslen, Cheryl, Edelman, Alison
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2014
Konular:
Short Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935138/
https://ncbi.nlm.nih.gov/pubmed/24368832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.054346
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