Biomarkers of Histone Deacetylase Inhibitor Activity in a Phase 1 Combined-Modality Study with Radiotherapy

BACKGROUND: Following the demonstration that histone deacetylase inhibitors enhanced experimental radiation-induced clonogenic suppression, the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study, combining fractionated radiotherapy with daily vorinostat for pelvic carcinoma, was designed to evalu...

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Detalhes bibliográficos
Main Authors: Ree, Anne Hansen, Saelen, Marie Grøn, Kalanxhi, Erta, Østensen, Ingrid H. G., Schee, Kristina, Røe, Kathrine, Abrahamsen, Torveig Weum, Dueland, Svein, Flatmark, Kjersti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934935/
https://ncbi.nlm.nih.gov/pubmed/24587009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089750
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