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Phosphorylation induces a decrease in the biological activity of the protein inhibitor (GABA-modulin) of gamma-aminobutyric acid binding sites.

gamma-Aminobutyric acid (GABA)-modulin is a brain protein of Mr 16,500 that down-regulates the high-affinity binding site for GABA which is located in crude synaptic membranes. This protein can be phosphorylated in vitro by the catalytic subunit of cAMP-dependent protein kinase and by a partially pu...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wise, B C, Guidotti, A, Costa, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298780/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.3.886
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