Immune Escape Mutants of Highly Pathogenic Avian Influenza H5N1 Selected Using Polyclonal Sera: Identification of Key Amino Acids in the HA Protein

Evolution of Avian Influenza (AI) viruses – especially of the Highly Pathogenic Avian Influenza (HPAI) H5N1 subtype – is a major issue for the poultry industry. HPAI H5N1 epidemics are associated with huge economic losses and are sometimes connected to human morbidity and mortality. Vaccination (eit...

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Main Authors: Sitaras, Ioannis, Kalthoff, Donata, Beer, Martin, Peeters, Ben, de Jong, Mart C. M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934824/
https://ncbi.nlm.nih.gov/pubmed/24586231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084628
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