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Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus.

Antinative DNA antibodies were purified from the serum of a patient with active systemic lupus erythematosus. Using hybridoma technology, we produced several mouse monoclonal antibodies directed against idiotypic determinants on these antinative DNA antibodies. One of these monoclonal anti-idiotypic...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Solomon, G, Schiffenbauer, J, Keiser, H D, Diamond, B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6187005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.3.850
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