IL-27 Activates Human Trophoblasts to Express IP-10 and IL-6: Implications in the Immunopathophysiology of Preeclampsia

Purpose. To investigate the effects of IL-27 on human trophoblasts and the underlying regulatory signaling mechanisms in preeclampsia. Methods. The expression of IL-27 and IL-27 receptor (WSX-1) was studied in the placenta or sera from patients with preeclampsia. In vitro, we investigated the effect...

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Main Authors: Yin, Nanlin, Zhang, Hua, Luo, Xin, Ding, Yubin, Xiao, Xiaoqiu, Liu, Xiru, Shan, Nan, Zhang, Xuemei, Deng, Qinyin, Zhuang, Baimei, Qi, Hongbo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934746/
https://ncbi.nlm.nih.gov/pubmed/24659862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/926875
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