Mos/mitogen-activated protein kinase can induce early meiotic phenotypes in the absence of maturation-promoting factor: a novel system for analyzing spindle formation during meiosis I.

Mitogen-activated protein kinase (MAPK) is selectively activated by injecting either mos or MAPK kinase (mek) RNA into immature mouse oocytes maintained in the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IBMX). IBMX arrests oocyte maturation, but Mos (or MEK) overexpression overrides th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Choi, T, Rulong, S, Resau, J, Fukasawa, K, Matten, W, Kuriyama, R, Mansour, S, Ahn, N, Vande Woude, G F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4730
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