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A Nicotinic Acetylcholine Receptor Agonist Prevents Loss of Retinal Ganglion Cells in a Glaucoma Model

PURPOSE. The purpose of this study was to analyze the neuroprotective effect of an α7 nAChR agonist, PNU-282987, using an in vivo model of glaucoma in Long Evans rats. METHODS. One eye in each animal was surgically manipulated to induce glaucoma in control untreated animals and in animals that were...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iwamoto, Kazuhiro, Birkholz, Patrick, Schipper, Austin, Mata, David, Linn, David M., Linn, Cindy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934540/
https://ncbi.nlm.nih.gov/pubmed/24458148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12688
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