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Mifepristone Decreases Depression-Like Behavior and Modulates Neuroendocrine and Central Hypothalamic-Pituitary-Adrenocortical Axis Responsiveness to Stress

Glucocorticoid dyshomeostasis is observed in a proportion of depressed individuals. As a result, glucocorticoid receptor (GR) antagonists are currently being tested as potential anti-depressants. The current study was designed to test the efficacy of mifepristone, a GR antagonist, in mitigating beha...

詳細記述

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書誌詳細
主要な著者: Wulsin, Aynara C., Herman, James P., Solomon, Matia B.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934351/
https://ncbi.nlm.nih.gov/pubmed/20149549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2010.01.011
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