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Characterization of the monoamine carrier of chromaffin granule membrane by binding of [2-3H]dihydrotetrabenazine.

[2-3H]Dihydrotetrabenazine (2-hydroxy-3-isobutyl-9, 10-dimethoxy-1,2,3,4,6,7-hexahydro-11b-H-benzo [a]-quinolizine), a derivative of the neuroleptic tetrabenazine, binds to the membrane of purified bovine chromaffin granules. Specific binding was characterized by Kd and Bmax values of 3.1 nM and 62...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Scherman, D, Jaudon, P, Henry, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6572908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.2.584
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