Blood transfusions with high levels of contaminating soluble HLA-I correlate with levels of soluble CD8 in recipients’ plasma; a new control factor in soluble HLA-I-mediated transfusion-modulated immunomodulation?

BACKGROUND: The cause of transfusion-related immunomodulation (TRIM) has proved tantalisingly elusive. An ever-growing body of evidence indicates that the infusion of large amounts of soluble and cell-associated antigens into a recipient can somehow induce TRIM. One soluble molecule that has been im...

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Detalhes bibliográficos
Main Authors: Ghio, Massimo, Contini, Paola, Ubezio, Gianluca, Ansaldi, Filippo, Setti, Maurizio, Tripodi, Gino
Formato: Artigo
Idioma:Inglês
Publicado em: Edizioni SIMTI - SIMTI Servizi Srl 2014
Assuntos:
Transfusion Medicine and Transfusion Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934222/
https://ncbi.nlm.nih.gov/pubmed/23356971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2012.0199-12
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