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An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo

The phagocytosis of apoptotic cells (ACs), or efferocytosis, by DCs is critical for self-tolerance and host defense. Although many efferocytosis-associated receptors have been described in vitro, the functionality of these receptors in vivo has not been explored in depth. Using a spleen efferocytosi...

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Detalhes bibliográficos
Main Authors: Subramanian, Manikandan, Hayes, Crystal D., Thome, Joseph J., Thorp, Edward, Matsushima, Glenn K., Herz, Joachim, Farber, Donna L., Liu, Kang, Lakshmana, Madepalli, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934164/
https://ncbi.nlm.nih.gov/pubmed/24509082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72051
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