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Single Tryptophan and Tyrosine Comparisons in the N-terminal and C-terminal Interface Regions of Transmembrane GWALP Peptides()

Hydrophobic membrane-spanning helices often are flanked by interfacial aromatic or charged residues. In this paper we compare the consequences of single Trp → Tyr substitutions at each interface for the properties of a defined transmembrane helix, in the absence of charged residues. The choice of mo...

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Autors principals: Gleason, Nicholas J., Greathouse, Denise V., Grant, Christopher V., Opella, Stanley J., Koeppe, Roger E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934079/
https://ncbi.nlm.nih.gov/pubmed/24111589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp407542e
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