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B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the CNS
The efficacy of rituximab treatment in multiple sclerosis has renewed interest in the role of B cells in CNS autoimmunity. Here we show that B cells are the predominant MHC class II(+) subset in the naïve CNS in mice, and they constitutively express pro-inflammatory cytokines. Incidence of experimen...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934009/ https://ncbi.nlm.nih.gov/pubmed/24367024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302171 |
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