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B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the CNS

The efficacy of rituximab treatment in multiple sclerosis has renewed interest in the role of B cells in CNS autoimmunity. Here we show that B cells are the predominant MHC class II(+) subset in the naïve CNS in mice, and they constitutively express pro-inflammatory cytokines. Incidence of experimen...

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Sonraí Bibleagrafaíochta
Main Authors: Pierson, Emily R., Stromnes, Ingunn M., Goverman, Joan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934009/
https://ncbi.nlm.nih.gov/pubmed/24367024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302171
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